Dr Paddy Barrett is committed to the prevention and treatment of heart disease.

Originally from Galway, Dr Barrett completed his medical school training at the University College Dublin. In combination with his cardiology training at the Royal College of Physicians of Ireland he has acquired extensive specialty cardiology training in world class medical centres in New York and California.

Dr Barrett spent four years at The Scripps Translational Science Institute in California working alongside the world renowned cardiologist Dr Eric Topol on the fields of cardiovascular genomics and medical innovation. As part of Dr Barrett's time there he played a pivotal role in the development of several novel technologies, large scale clinical trials and has published extensively in the field. He speaks regularly around the world on heart disease.

As part of Dr Barrett's interventional cardiology training he spent a year at Columbia University Medical Center in New York City working with the pioneers of numerous cardiovascular procedures and served as a Faculty member of TCT.

In collaboration with NASA's Reduced Gravity Office, Dr Barrett flew several campaigns validating medical devices in the zero gravity environment. This work was sponsored by NASA and forms part of their work to allow future astronauts be medically monitored in the space environment.


Dr Barrett is also the founder and host of the internationally acclaimed medical podcast 'The Doctor Paradox' which explores the growing issue of physician burnout. As part of his work on physician wellness, Dr Barrett is a much sought after speaker on the topic around the world. Additionally Dr Barrett serves as a Faculty Member of the medical education company, Practicing Excellence which provides physician education to hospital systems across the United States. His work on physician performance has resulted in collaboration with a host of medical and scientific thought leaders.

Dr Paddy Barrett with Dr Eric Topol displaying hand-held smartphone ultrasound technologies which are likely to replace the use of the stethoscope in clinical practice in the future.

paddy headspace

Dr Barrett has also worked with the worlds most famous online meditation service, Headspace, founded by the Bhuddist Monk Andy Puddicombe.

Dr Paddy Barrett with Dr Deepak Chopra at the Sages & Scientists Conference, Beverly Hills, Los Angeles discussing his role in physician wellness.


As part of Dr Barrett's work on medical innovation he is a regular speaker around the world on how technology will influence future of healthcare. 

Awards & Recognitions

  • 40 Under 40 Irish Echo New York - Winner
  • Boston Scientific Fellows Masters Program - Winner
  • Irish Cardiac Society - Young Investigators Award - Finalist
  • NASA Flight Opportunities Program. Zero Gravity Campaign, Texas
  • A Menarini Traveling Research Scholarship
  • McArdle Prize in Surgery - Winner
  • O'Farrell Gold Medal in Surgery - Finalist 
  • Tobin Medal in Surgery - Finalist

Selected Publications


  • Barrett PM, Muse E, Steinhubl S, Topol EJ. Digitizing The Mind. The Lancet. May 2017
  • Muse E, Kramer E, Haiyang W, Barrett PM, Topol EJ. A Whole Blood Molecular Signature For Acute Myocardial Infarction. Scientific Reports. Sept 2017
  • Steinhubl S, Muse E, Barrett PM, Topol EJ. Digital Medicine. Off the cuff: rebooting blood pressure treatment. The Lancet. Sept 2016
  • Barrett PM, Topol EJ. Smartphone Medicine. IEEE. April 2016
  • Barrett PM, Topol EJ. To Truly Look Inside. The Lancet. April 2016
  • Bloss C, Wineinger N… Barrett PM… Topol EJ. A prospective randomized trial examining health care utilization in individuals using multiple smartphone-enabled biosensors. PeerJ 
  • ED Muse, H Wang, P Barrett, Topol EJ. A molecular signature with the potential for identifying impending acute myocardial infarction. Circulation 130 (Suppl 2), A13338-A13338
  • Komatireddy R, Barrett PM, Muse ED. Wired for takeoff. N Engl J Med. 2013; Aug 29;369(9):876-7.
  • Ansary A, Azuma A, Komatireddy R, Barrett PM. The world of connected health in cardiology. QJM. 2013 Aug 5. [Epub ahead of print]
  • Barrett PM, Komatireddy R, Topol EJ. Comparison of 24 hour Holter monitoring versus 14 day novel adhesive patch electrocardiographic monitoring. American Journal of Medicine 127 (1), 95.e11-95. e17
  • Barrett PM, Price MJ. Pharmacogenomics in the field of interventional pharmacology: present status and future directions. Interventional Cardiology Clinics. (In press)
  • Barrett PM, Topol EJ. Pharm-Econogenomics. A New Appraisal. Journal of Clinical Chemistry. 2013 Apr;59(4):592-4.
  • Grazette L, Paltoo D, McDevitt JT, Barrett PM, Rao A, Libby P. NHLBI Working Group: Onsite Tools and Technologies for Clinical Cardiovascular Research and Point-of-Care. Journal of the American College of Cardiology: Basic To Translational Science. Vol 1. 73-86 Feb 2016.
  • Barrett PM, Alagely A, Topol EJ. Cystic fibrosis in an era of genomically guided therapy.
  • Human Molecular Genetics. 2012 Oct 15;21(R1):R66-71
  • Barrett PM, Topol EJ. The fibrillin-1 gene: Unlocking new therapeutic pathways in cardiovascular disease. Heart. 2013 Jan;99(2):83-90.
  • Barrett PM, Topol EJ. Pharmacogenetics: Point-of-care genetic testing – a new frontier explored. Nature Reviews Cardiology. 2012 May 1;9(6):315-6
  • Barrett PM, Lu J, Topol EJ. Point of Care Detection of Circulating Microparticles and Cell Free DNA in Patients With Acute Myocardial Infarction. Journal of the American College of Cardiology. 2013;61(10_S)
  • Barrett PM, Topol EJ. Gene expression analysis of circulating endothelial cells in acute myocardial infarction. European Heart Journal. Aug 2012 33(suppl 1): 655-939
  • Feeney S, Muldoon E, Barrett PM, Martis R, Mulvihill N, O’Flanagan D, Bergin C. Varicella infection and the impact of late entry into the Irish healthcare system. Journal of Infection and Public Health. Sept 2010;3(3):106-12.
  • Barrett PM, Stack A. Prevalence, period trends and survival trends of dialysis patients with peripheral artery disease in the United States: 1995 – 2004. European Heart Journal. Sept 2010 31(suppl 1): 1-1150
  • Ho E, Brown A, Barrett PM, Murphy RT. Subclinical anthracycline- and trastuzumab-induced cardiotoxicity in the long term follow-up of asymptomatic breast cancer survivors: a speckle tracking echocardiographic study. Heart. 2010 May;96(9):701-7
  • Ho E, Brown A, Barrett PM, Murphy RT. Determinants of two dimensional speckle tracking echocardiography-derived longitudinal and radial strain in anthracycline and trastuzumab chemotherapy breast cancer survivors. Irish Journal of Medical Science. 2009 Oct;178 Suppl 9:S349-79
  • Ho E, Barrett PM, Murphy RT. Effects of anthracycline and trastuzumab therapy on myocardial strain in asymptomatic breast cancer patients – a tissue speckle tracing study. European Heart Journal. 2008 Sept:29 Suppl 1:3-900
  • Clarke B, Barrett PM, Kale V, Conway M. To cardiovert or not to cardiovert? Irish Journal of Medical Science. 2008 Sept:177 Suppl 9:S303-50.
  • Barrett PM, O’Sullivan MJ, Hill ADK. Pre-operative pathological evaluation of the axilla can reduce the re-operation rate in node positive breast cancer. British Journal of Surgery. 2006 July 2006 :93 Suppl 3 1-57